One of the main signs and symptoms of obesity is insulin resistance. In a healthy body, when glucose is absorbed in the stomach and into the bloodstream, the pancreases releases insulin to aid in the absorption of glucose into the cells. Where eating patterns are characterized by an excessive supply of glucose, the body cells are unable to respond to insulin production thereby take up glucose and use it for energy production. This results in insulin resistance.
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CBD’s effect on homeostasis is believed to be why those in need of nutrition can experience an appetite increase and those with excess weight can experience an appetite decrease. The reason for this is that CBD is an adaptogen. Referred to by some scientists as “the boy scout molecule” because it always does the right thing in any given situation. The Journal of Psychopharmacology tested this theory on rats in 2012. The researchers wanted to see how three common cannabinoids, including CBN, CBD, and CBG, affected the appetite of the rats. The study concluded that both CBD and CBG worked to reduce the rat’s appetite.